Lewy Body Disease

Lewy bodies are hallmark pathological features found in the neurons of people with Parkinson's disease. They also appear to play a role in other neurodegenerative disorders that cause dementia. Cortical Lewy-body disease refers to a dementia that presents with Parkinsonian motor symptoms (primarily rigidity and gait 68, disorder), as well as fluctuating attention and alertness, visual hal lucinations, delusional thinking, and other psychiatric and behavioral features.

The primary initial neuropsychological findings are found in the realms of attention and high-order visual processing, such as analysis of complex images and the ability to draw designs and assemble puzzles. Although performance on memory testing is rarely normal, memory impairment is not the most prominent cognitive finding, particularly in the early phase. The relationship between Lewy bodies and dementia is not yet clear, and the overlap with Alzheimer's disease has made reliable diagnosis of this disorder difficult and somewhat controversial. One school of thought is that most people with Lewy-body dementia also have Alzheimer's disease.

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