Pdapp

Human APP V717F PDGF promotor

Yes

Partial (98)

Minimal

Water maze Spatial series (99) Object recognition (95) Holeboard (95)

Tg2576+JNPL 3

APPswe P301L Tau

Yes

Yes (100)

Minimal

?

TgLRND8

Human APP 670N/671L + V717F

(+M146L L286V PS-1 mutant)

Plaques accelerated

Minimal

Minimal

Water maze (93, 101)

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