Biochemical Mechanisms for Long Term Information Storage at the Cellular Level

Introduction I. The Case for Altered Gene Expression in L-LTP II. Signaling Mechanisms

A. A Core Signal Transduction Cascade Linking Calcium to the Transcription Factor CREB

B. Modulatory Influences That Impinge Upon This Cascade

C. Additional Transcription Factors Besides CREB That May Be Involved in L-LTP Induction

D. Gene Targets in L-LTP

E. mRNA Targeting and Transport

F. Effects of the Gene Products on Synaptic Structure III. Summary

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