Metals like chromium, magnesium, and selenium compete with aluminum in some of their actions because they occupy similar positions in the periodic table of natural elements. The interest in these elements accelerated after the aluminum theory of Alzheimer's disease was proposed. In the early 1980s, traces of aluminum were found in the plaques and tangles that develop in the brains of patients with Alzheimer's disease. However, community surveys across the world show no link between aluminum exposure and dementia, or even milder forms of memory loss. As a result, research in this area has floundered in recent years. Few studies have been conducted with any of these metals as a treatment for memory loss.

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